Transcatheter injectable embolic agent for minimally invasive vascular intervention
Speaker: Dr. Jingjie Hu
Assistant Professor at North Carolina State University
When: April, 03, 2025 | 10:00 AM – 11:00 AM
Location: Civil and Mechanical Engineering Building (CEME), room 1203 (6250 Applied Science Lane, Vancouver)
Zoom: https://ubc.zoom.us/j/97206574075?pwd=b0tpc3czNmV0YmJ5dUhmcGwya0RjZz09
This talk is part of the Structural Matter Seminar Series.
Abstract:
Minimally invasive embolization relies on embolic agents such as metallic coils, microspheres, and liquid embolics, which are available in clinical practice. While effective, these agents face limitations like imprecise deployment, migration, or catheter occlusion. Shear-thinning materials offer a novel alternative, transitioning from a high-viscosity gel to a fluid under shear stress, enabling smooth catheter delivery while solidifying post-deployment for stable occlusion. This work develops a gel embolic agent with tunable shear-thinning properties, optimizing key mechanical characteristics—storage modulus, yield stress, and thixotropy—for enhanced clinical performance. Transcatheter injectability were evaluated to improve delivery predictability and physician control.
Biography:
Jingjie Hu is an Assistant Professor in the Department of Mechanical and Aerospace Engineering at North Carolina State University. She earned her PhD in mechanical engineering from Princeton University and completed her postdoctoral research in translational bioengineering at Mayo Clinic. Her work explores the mechanical behavior of biomedical and biological materials, bridging engineering and medicine to advance applications in cancer detection and vascular embolization.